Repeated measures screening for Down's Syndrome

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Repeated measures screening for Down's Syndrome.

OBJECTIVE To demonstrate the potential value of screening for Down's Syndrome using highly correlated repeated measures of serum markers taken in the first and second trimesters of pregnancy. DESIGN A Monte Carlo simulation study. POPULATION Detection rates and false positive rates relating to the maternal age distribution of England and Wales for the period 1996 to 1998 were obtained using...

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Cross-trimester repeated measures testing for Down's syndrome screening: an assessment.

OBJECTIVES To provide estimates and confidence intervals for the performance (detection and false-positive rates) of screening for Down's syndrome using repeated measures of biochemical markers from first and second trimester maternal serum samples taken from the same woman. DESIGN Stored serum on Down's syndrome cases and controls was used to provide independent test data for the assessment ...

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Repeated Measures

Repeated measures refer to the observations taken on the same subject (plant, animal, person, etc). There is usually a variation among the subjects, which is modeled by random effects. Here is an example. A completely randomized design with a single factor (with fertilizer or without). Each treatment is applied to three plants and the root length of each plant is measured on five occasions (wee...

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Repeated measures.

A repeated-measures design is one in which multiple, or repeated, measurements are made on each experimental unit. The experimental unit could be a person or an animal, and repeated measurements might be taken serially in time, such as in weekly systolic blood pressures or monthly weights. The repeated assessments might be measured under different experimental conditions. Repeated measurements ...

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Repeated screening for breast cancer.

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ژورنال

عنوان ژورنال: BJOG: An International Journal of Obstetrics and Gynaecology

سال: 2005

ISSN: 1470-0328,1471-0528

DOI: 10.1111/j.1471-0528.2004.00343.x